In Vitro Antiviral Activity of α-Mangostin against Dengue Virus Serotype-2 (DENV-2)
نویسندگان
چکیده
منابع مشابه
Antiviral Activity of Novel Quinoline Derivatives against Dengue Virus Serotype 2.
Dengue virus causes dengue fever, a debilitating disease with an increasing incidence in many tropical and subtropical territories. So far, there are no effective antivirals licensed to treat this virus. Here we describe the synthesis and antiviral activity evaluation of two compounds based on the quinoline scaffold, which has shown potential for the development of molecules with various biolog...
متن کاملPhage-Displayed Peptides Selected to Bind Envelope Glycoprotein Show Antiviral Activity against Dengue Virus Serotype 2
Dengue virus is a growing public health threat that affects hundreds of million peoples every year and leave huge economic and social damage. The virus is transmitted by mosquitoes and the incidence of the disease is increasing, among other causes, due to the geographical expansion of the vector's range and the lack of effectiveness in public health interventions in most prevalent countries. So...
متن کاملIn vitro antiviral activity of Fisetin, Rutin and Naringenin against Dengue virus type-2
In vitro antiviral activities of three flavonoids; fisetin, naringenin and rutin against DENV-2 (NGC strain) were evaluated. Inhibitory effects of each compound at the different stages of DENV-2 infection were examined using foci forming unit reduction assay (FFURA) and quantitative real-time polymerase chain amplification (qRT-PCR). Fisetin, rutin and naringenin showed cytotoxic effects agains...
متن کاملOutbreak of dengue virus serotype-2 (DENV-2) of Cambodian origin in Manipur, India - Association with meteorological factors
BACKGROUND & OBJECTIVES Dengue is a major health problem in many parts of India and its neighbouring countries. Dengue cases have not been reported from Manipur, a northeastern State of India till 2007. But, the sudden outbreak of fever with febrile illness during 2007 and 2008, suspected to be dengue/dengue haemorrhagic fever was investigated to detect the causative agent. Potential impact of ...
متن کاملDengue Fever Virus (DENV)
The name of the disease is said to be derived from the Portuguese word dengue which means fastidious or vain, which would describe the disturbed gait of an infected person suffering from muscle and bone pain (see also English: ‘dandy’). Dengue virus and dengue haemorrhagic fever virus are synonyms. The dengue fever virus (DENV) is a member of the genus of the 53 flaviviruses and ranks among the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecules
سال: 2021
ISSN: 1420-3049
DOI: 10.3390/molecules26103016